Finlands Akademi  
Sökande / Kontakt person Hytönen, Vesa
Organisation Tammerfors universitet
Projektets titel MechanoToolKit: Molecular tools for cellular mechanobiology
Beslutnr 331946
Beslutsdatum 27.05.2020
Finansierings period 01.09.2020 - 31.08.2024
Finansiering 525 243
Beskrivning av projektet
Mechanical signals are essential for our health, but very little is known about the molecular mechanisms behind mechanosensing. The proposed research project aims to develop better tools to detect the changes in protein function due to mechanical signals. We utilize engineered proteins to reveal mechanosignaling events in living cells and aim to reprogram cells to sense their environment in predetermined fashion. Better understanding of cellular mechanosensing would help us to understand diseases such as cancer metastasis.