Finlands Akademi  
Sökande / Kontakt person Visakorpi, Tapio
Organisation Tammerfors universitet
Projektets titel Role of long non-coding RNAs in Prostate Cancer
Beslutnr 317755
Beslutsdatum 03.05.2018
Finansierings period 01.09.2018 - 31.08.2022
Finansiering 450 000
Beskrivning av projektet
Prostate cancer is the most common malignancy among men in Western countries and second most cause of cancer-related deaths. The three unmet needs in treatment of prostate cancer are 1) how to identify patients who needs active treatment, 2) how to choose the best possible treatment, and 3) how to improve treatment for the aggressive disease form. Long non-coding RNAs (lncRNAs) are new molecules whose function and significance in prostate cancer are poorly understood. Here, we will identify lncRNAs that are overexpressed in prostate cancer, the mechanisms of the overexpression and their significance in cancer. We will utilize our unique sample biorepository and our skills in genomics. The aim is to find out whether lncRNAs could function as biomarkers or drug targets.