Finlands Akademi  
Sökande / Kontakt person Paju, Susanna
Organisation Helsingfors universitet
Projektets titel Periodontitis and dental intervention in coronary heart disease and cryptogenic stroke
Beslutnr 316777
Beslutsdatum 03.05.2018
Finansierings period 01.01.2019 - 31.08.2022
Finansiering 450 000
Beskrivning av projektet
Oral bacteria and oral health status may influence the course of atherosclerosis by inducing systemic inflammation that may subsequently predispose to cardiovascular conditions. The objective is to find evidence on periodontal infection and oral bacteria contributing to the occurrence of cardiovascular diseases. Clinical, microbiologic, and radiological oral examinations will include two patient populations. Patients with angiographically verified coronary artery disease will be examined in a longitudinal ten year follow-up study and the dental intervention will be found out in their dental records. Patients with cryptogenic stroke and their matched controls will be investigated in a case-control study. This project will provide novel information on clinical oral risk factors for cardiovascular diseases. The relevance of the studies is to emphasize the importance of periodontal health and improved oral care. The aim on this project funding is to start an own research group.