Finlands Akademi  
Sökande / Kontakt person Kursula, Petri
Organisation Uleåborgs universitet
Projektets titel GDAP1 - an enigmatic enzyme linked to inherited peripheral neuropathy
Beslutnr 315272
Beslutsdatum 03.05.2018
Finansierings period 01.09.2018 - 31.08.2022
Finansiering 450 000
Beskrivning av projektet
Axons in the peripheral nervous system can be up to 1 m long, and their development and function require efficient energy metabolism. Hereditary motor and sensory neuropathies, known as CMT, affect both peripheral neurons and Schwann cells. The mitochondrial protein GDAP1 is commonly mutated in human CMT. We aim to understand the molecular level basis for diseases that involve mutations in GDAP1.