Academy of Finland
Funding decision
 
Applicant / Contact person Kekäläinen, Jukka
Organisation University of Eastern Finland
Project title Towards molecular-level understanding of fertilization and sexual selection
Decision No. 327509
Decision date 03.12.2019
Funding period 01.01.2020 - 31.12.2022
Funding 245 892
WebFOCUS Report
Project description
Fertilization is one of the most complex and enigmatic biological processes, which severely hinders our understanding about reproduction, evolution and beginning of life. It has traditionally been assumed that fertilization is a completely unbiased process, leading to random fusion of gametes, which is also a key foundation of modern genetics. Against this assumption, our recent findings have indicated that gametes often combine non-randomly, which bias fertilization towards particular (compatible) reproductive partners. However, the molecular-level mechanisms of the process have remained unclear. The primary aim of this research is to produce new information about these fundamentally important key regulatory mechanisms of life in humans.