Academy of Finland  
Funding decision
Applicant / Contact person Huiskonen, Juha T
Organisation University of Helsinki
Project title Structures of Endogenous of Macromolecular Assemblies
Decision No. 314669
Decision date 18.06.2018
Funding period 01.09.2018 - 31.08.2022
Funding 379 076
Project description
Structures of biological macromolecules can reveal us the molecular basis of cellular functions and disease. We will develop technologies for capturing human proteins directly from cell lines for their structure determination. We will test and apply the developed methods to study several targets involved in human protein homeostasis, a control mechanism in every living cell. We expect the novel technologies to be widely applicable in studying basic biomolecular mechanisms and disease and offer potential for commercialization.