Academy of Finland
Funding decision
Name Nissinen, Ilkka
Organisation OY
Project title Single-photon detector array for simultaneous label-free Raman and fluorescence lifetime spectroscopy
Decision No. 314404
Decision date 20.11.2017
Funding period 01.01.2018 - 31.12.2021
Funding 488 564
WebFOCUS Report
Project description
Raman and fluorescence lifetime spectroscopies are commonly used methods to resolve the chemical content of material. Raman signal provides spectral fingerprint based on the low frequency vibrational modes of a molecule, and fluorescence lifetime originates from the relaxation time of excited electrons of a molecule. Combining fluorescence lifetime and Raman spectra offers more powerful method for material analysis than either of them alone. In this project a single photon avalanche diode array with time-to-digital converter array will be developed to measure both the fluorescence free Raman and fluorescence lifetime spectra of high fluorescent biological samples simultaneously with a pulsed laser. The detector measures accurate time domain photon distributions from which the both spectra can be derived. This detector can be used for a remote multipoint spectrometer for label free pharmaceutical and industrial process control to increase safety issues, especially in toxic processes.