Academy of Finland
Funding decision
Name Nieminen, Miika
Organisation OY
Project title
Multiparametric MRI assessment of osteoarthritis
Decision No. 260321
Decision date 11.04.2012
Funding period 01.09.2012 - 31.08.2016
Funding 450 000
WebFOCUS Report
Project description
In this research project, novel quantitative MRI techniques for the early detection of osteoarthritis were developed. Using experimental models, novel rotating frame of reference relaxation techniques were demonstrated to be sensitive to early degeneration of articular cartilage in vitro. Following this, these methods were successfully implemented on a clinical MRI system and the sensitivity for cartilage degeneration was demonstrated. Furthermore, the novel methods were associated with early cartilage degeneration and early symptoms of osteoarthritis.