The overarching aim of our multidisciplinary project is to study how conditions during sensitive periods of fetal life, infancy and puberty predict health in adult life. We study two birth cohorts: The Helsinki Birth Cohort (Births 1924-1934; n=20431) and Arvo Ylppö Longitudinal Study (1985-1986; n=2193). Much of the research is based on data already collected; we comlement these data by inviting participants in the Arvo Ylppö Study to a detailed clinical examination. Our specific aims are: 1) To study how growth during sensitive developmental periods predicts a) cognitive functioning; b) depression; c) cardiovascular disease; d) type 2 diabetes.
2) To study how common pregnancy disorders, childhood diseases and socioeconomic and lifestyle factors affect these associations.
3) To study how normal genetic variation between individuals affects these associations.